Ampicillin with Sulbactum

-Ampicillin with sulbactam is used to treat a wide range of bacterial infections. Ampicillin belongs to a group of antibiotic medications known as penicillin, while sulbactam belongs to beta-lactamase inhibitor drugs. In combination, they kill the bacteria and inhibit the growth of bacteria. -Ampicillin with Sulbactam is a combination antibiotic that comprises ampicillin, a broad-spectrum penicillin, and sulbactam, a beta-lactamase inhibitor. This combination enhances the antimicrobial activity of ampicillin by preventing the inactivation of the antibiotic by beta-lactamase enzymes.

Indications

-Respiratory tract infections -Skin and soft tissue infections -Intra-abdominal infections -Urinary tract infections -Gynecological infections -Bacterial meningitis -Urinary tract infection -Skin diseases -Acute appendicitis -Diverticulitis -Pancreatitis -Cholecystitis Chlamydia -Herpes.

Dosage

Dosage may vary based on the severity of the infection and patient characteristics. Always follow the prescribed dosage and administration schedule provided by a healthcare professional.

Contra-Indications

-Known hypersensitivity to penicillins or beta-lactamase inhibitors -History of severe allergic reactions to any beta-lactam antibiotic -Hypersensitivity to ampicillin or sulbactam, kidney diseases, and ulcers.

Special Precautions

-Patients with a history of allergic reactions -Renal impairment -Gastrointestinal diseases, especially colitis -Inform healthcare provider of any previous adverse reactions to antibiotics -It is recommended to consult a healthcare professional before using it in pregnancy and breastfeeding.

Side Effects

-Common side effects may include diarrhea, nausea, vomiting, rash, and allergic reactions. Consult a healthcare professional if any side effects persist or worsen. -Allergic reactions, community-acquired pneumonia (CAP), diarrhoea, abdominal pain, vomiting, dizziness, weakness, and breathlessness.

Drug Interactions

-Probenecid may increase the concentration of ampicillin and sulbactam -Concurrent use with aminoglycosides may enhance antibacterial activity -Methotrexate toxicity may increase when used concurrently -Anticancer drugs, antiplatelet drugs, contraceptives, antigout drugs and similar antibiotics.