Carboplatin
Carboplatin is a chemotherapy drug used to treat various types of cancer, including ovarian cancer, lung cancer, and testicular cancer. It works by interfering with the DNA in cancer cells, preventing them from growing and multiplying.-Ovarian cancer -Non-small cell lung cancer -Testicular cancer -Certain types of brain cancer -Other cancers as determined by a healthcare provider
The dosage of Carboplatin depends on the type of cancer being treated, the patient’s overall health, and other factors. It is typically administered intravenously. A common dosing regimen is based on the Calvert formula, which calculates the dose based on the patient's renal function and body surface area.
-Hypersensitivity to Carboplatin or other platinum-containing compounds -Severe bone marrow suppression -Severe renal impairment
-Monitor renal function regularly, as Carboplatin can affect kidney function. -Be cautious in patients with a history of severe allergic reactions. -Monitor blood counts closely due to the risk of myelosuppression.
-Nausea and vomiting -Fatigue -Loss of appetite -Hair loss -Anemia -Thrombocytopenia (low platelet count) -Neutropenia (low white blood cell count) -Possible kidney damage
-Enhanced toxicity with other nephrotoxic drugs (e.g., cisplatin, aminoglycosides) -May increase the risk of bleeding with anticoagulants (e.g., warfarin) -Potential interaction with drugs that affect kidney function or are metabolized by the liver
