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Cefixime with Azithromycin- dose, indications, adverse effects, interactions

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Cefixime with Azithromycin

Cefixime with Azithromycin

Cefixime and Azithromycin are both antibiotics used to treat various bacterial infections. Cefixime belongs to the cephalosporin class, while Azithromycin is a macrolide antibiotic. Combining these two antibiotics may be prescribed in certain situations to provide a broader spectrum of coverage against different types of bacteria.

Indications

This combination is commonly used to treat respiratory tract infections, urinary tract infections, sexually transmitted infections, and certain bacterial gastrointestinal infections.


Dosage

The dosage may vary based on the specific condition being treated. It is crucial to follow the healthcare provider's instructions. Dosage adjustments may be necessary for individuals with renal impairment.


Contra-Indications

Do not use this combination in individuals with known hypersensitivity to cephalosporins, macrolides, or any other components of the medications. Caution is advised in patients with a history of allergic reactions to antibiotics.


Special Precautions

-Use with caution in patients with renal impairment. -Monitor for signs of allergic reactions during treatment. -Inform healthcare providers of any pre-existing medical conditions or medications being taken.


Side Effects

Common side effects may include gastrointestinal disturbances (nausea, diarrhea), allergic reactions, and changes in liver function tests. Serious side effects are rare but may include severe skin reactions and pseudomembranous colitis.


Drug Interactions

-Cefixime may interfere with the absorption of certain drugs, such as antacids and iron supplements. -Use caution when combining with other medications that can prolong the QT interval, as Azithromycin may also have this effect.


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