Severity: Warning
Message: fopen(/var/cpanel/php/sessions/ea-php74/ci_session20f6ffa838a7caf0d3f7b43a7c67dd48122a2c3f): failed to open stream: No space left on device
Filename: drivers/Session_files_driver.php
Line Number: 176
Backtrace:
File: /home/drugtodayonline/public_html/application/controllers/Drug_directory.php
Line: 9
Function: __construct
File: /home/drugtodayonline/public_html/index.php
Line: 311
Function: require_once
Severity: Warning
Message: session_start(): Failed to read session data: user (path: /var/cpanel/php/sessions/ea-php74)
Filename: Session/Session.php
Line Number: 143
Backtrace:
File: /home/drugtodayonline/public_html/application/controllers/Drug_directory.php
Line: 9
Function: __construct
File: /home/drugtodayonline/public_html/index.php
Line: 311
Function: require_once
CYCLOSPORINE
It is a cyclic polypeptide containing 11 amino acids. It suppresses humoral immunity and to a great extent, cell-mediated reactions. This action is due to a specific and reversible inhibition of immunocompetent lymphocytes in the G0 or G1 phases of cell cycle. T-helper cells are the main target but T-suppressor cells are also suppressed. Cyclosporine also inhibits lympholine production and release.Orally used for prevention of graft rejection after kidney, liver, heart, lung, pancreas. By IV infusion used in bone marrow transplant.
Oral: First dose given 4-12 hrs. before the transplantation, 10-15 mg/kg. This dose in continued daily for 1-2 weeks after which a maintenance dose of 2-6 mg/kg/day is continued. IV infusion: Starting dose one day before the transplantation 3-5 mg/kg/day. Continue for 2 weeks after transplant. Then oral maintenance dose of 12.5 mg/kg/day in 2 divided doses for 6 months to a year.
Hypersensitivity, lactation.
Dose should be carefully titrated. Renal and/or hepatic impairment, possibility of hyperkalaemia, hypertension, vaccinations are less effective. Paediatrics: Use with caution. Pregnancy: Safety has not been established. Lactation: Safety has not been established. Elderly: Reduced dose may be necessary.
Kidney damage, convulsions, hypertension, liver damage, tremor, hirsutism, gingival hypertrophy, hyperkalaemia, fluid retention, increased susceptibility to infectons, GI symptoms.
Additive nephrotoxicity due to aminoglycosides, amphotericin B, ciprofloxacin, colchicine, melphalan, co-trimoxazole, NSAIDs. Cyclosporine blood levels increased by diltiazem, doxycycline, erythromycin, ketoconazole, methyl-prednisolone, nicardipine, verapamil, oral contraceptives. Carbamazepine, isoniazid, phenobarbitone, phenytoin, rifampicin reduce cyclosporine levels.
| Brand Name | Manufactured by |
|---|---|
| VAKTEAR EYE | DEVAK FORMULATIONS |
Severity: Warning
Message: mysqli::query(): (HY000/1): Can't create/write to file '/tmp/#sql_3e2_0.MYI' (Errcode: 28 - No space left on device)
Filename: mysqli/mysqli_driver.php
Line Number: 307
Backtrace:
File: /home/drugtodayonline/public_html/application/models/Site_ads_model.php
Line: 118
Function: query
File: /home/drugtodayonline/public_html/application/libraries/Common_lib.php
Line: 318
Function: get_front_ads_data
File: /home/drugtodayonline/public_html/application/views/front/salt_info.php
Line: 165
Function: common_footer_ads
File: /home/drugtodayonline/public_html/application/controllers/Drug_directory.php
Line: 331
Function: view
File: /home/drugtodayonline/public_html/application/controllers/Drug_directory.php
Line: 29
Function: drug_info
File: /home/drugtodayonline/public_html/index.php
Line: 311
Function: require_once
Severity: Warning
Message: Cannot modify header information - headers already sent by (output started at /home/drugtodayonline/public_html/system/core/Exceptions.php:271)
Filename: core/Common.php
Line Number: 570
Backtrace:
File: /home/drugtodayonline/public_html/application/models/Site_ads_model.php
Line: 118
Function: query
File: /home/drugtodayonline/public_html/application/libraries/Common_lib.php
Line: 318
Function: get_front_ads_data
File: /home/drugtodayonline/public_html/application/views/front/salt_info.php
Line: 165
Function: common_footer_ads
File: /home/drugtodayonline/public_html/application/controllers/Drug_directory.php
Line: 331
Function: view
File: /home/drugtodayonline/public_html/application/controllers/Drug_directory.php
Line: 29
Function: drug_info
File: /home/drugtodayonline/public_html/index.php
Line: 311
Function: require_once
Error Number: 1
Can't create/write to file '/tmp/#sql_3e2_0.MYI' (Errcode: 28 - No space left on device)
SELECT * FROM `dt_site_ads` WHERE `status` = '1' and `loc` = 'pre_footer_4' ORDER BY RAND() LIMIT 0,1
Filename: models/Site_ads_model.php
Line Number: 118