Dexrabeprazole with Domperidone

Dexrabeprazole is a proton pump inhibitor (PPI) that reduces the production of stomach acid. Domperidone is a dopamine antagonist that helps to improve gastrointestinal motility. This combination is used to treat conditions related to excessive stomach acid and impaired digestive function.

Indications

-Gastroesophageal Reflux Disease (GERD) -Peptic Ulcers -Dyspepsia -Gastroparesis (delayed gastric emptying) -Zollinger-Ellison Syndrome

Dosage

The dosage may vary based on the specific condition and individual response. Generally, a once-daily dose is recommended. It is crucial to follow the prescribed dosage and duration advised by a healthcare professional.

Contra-Indications

-Hypersensitivity to Dexrabeprazole, Domperidone, or any component of the formulation. -Patients with a history of cardiac arrhythmias or other cardiovascular conditions.

Special Precautions

-Patients with hepatic impairment should be monitored closely. -Caution in patients with renal impairment. -Avoid use in individuals with a history of cardiac diseases or QT prolongation. -Use with caution in pregnant and lactating women. -Pediatric use should be under strict medical supervision.

Side Effects

-Gastrointestinal disturbances (nausea, diarrhea) -Headache -Dizziness -Increased liver enzymes -Cardiac arrhythmias (rare)

Drug Interactions

-Increased risk of arrhythmias with drugs prolonging QT interval (e.g., certain antibiotics, antipsychotics). -Reduced absorption of Dexrabeprazole with antacids. -Enhanced sedative effects with central nervous system depressants.