Esomeprazole with Levosulpride
Esomeprazole is a proton pump inhibitor (PPI) that reduces stomach acid production. Levosulpiride is a dopamine antagonist with prokinetic properties, enhancing gastrointestinal motility. The combination aims to address acid-related disorders and associated motility issues.-Gastroesophageal Reflux Disease (GERD) -Peptic Ulcer Disease -Dyspepsia -Functional Dyspepsia with Delayed Gastric Emptying
Dosage may vary based on the specific condition and patient response. Typically, Esomeprazole 20-40mg and Levosulpiride 75-150mg are administered daily before meals. Adjustments should be made under medical supervision.
-Hypersensitivity to Esomeprazole or Levosulpiride -Severe liver impairment -Pregnancy and lactation
-Renal impairment - dose adjustment may be necessary. -Cardiovascular diseases - monitor for QT interval prolongation. -Neurological disorders - caution in patients with a history of seizures.
-Common: Headache, nausea, diarrhea -Rare: Hypersensitivity reactions, dizziness, arrhythmias
-Esomeprazole may interact with drugs metabolized by CYP2C19. -Levosulpiride may enhance the effects of central nervous system depressants.
