HEPARIN TOPICAL

It is useful in thrombo-embolic conditions. Refer to chapter on Cardiovascular system.

Indications

Haematomas. Superficial thrombo-phlebitis. Tenosynovitis. Sprains & bruises.

Contra-Indications

Do not apply to bleeding areas or eyes. Patch test for tolerance before use on chronic open lesions.

Special Precautions

Not for systemic use or application to mucus mebranes. Paediatrics: Reduced dose necessary. Pregnancy: Use with caution. Lactation: No evidence of risk. Elderly: No special problem.

Side Effects

Bleeding, rash, aching bones, thrombocytopenia, alopecia, anaphylaxis, rigor, slight haematuria. hypersensitivity reactions include urticaria, conjunctivitis, rhinitis, asthma, angioedema and anaphylactic shock, priapism.

Drug Interactions

Salicylates and dipyridamole enhances activity. Increased effec with oral anticoagulant Phenylbutazone, Streptokinase. Incompatible with aminoglycoside antibiotics. Antiplatelet drugs like aspirin may precipitate bleeding.