HUMAN ANTI-D IMMUNOGLOBULIN

Human Anti-D Immunoglobulin is a blood product used to prevent Rh immunization in Rh-negative individuals who are at risk of developing Rh antibodies. It works by providing passive immunity to prevent the production of antibodies against Rh-positive blood cells.

Indications

-Prevention of Rh sensitization in Rh-negative women during and after pregnancy -Treatment of hemolytic disease of the newborn due to Rh incompatibility -Post-abortion or post-delivery prophylaxis for Rh-negative women

Dosage

-Prenatal: Typically administered at 28 weeks of gestation. -Postpartum: Given within 72 hours after delivery if the baby is Rh-positive. -Post-abortion: Administered within 72 hours following a miscarriage or elective abortion if the patient is Rh-negative.

Contra-Indications

-Known hypersensitivity to immunoglobulin preparations -Active or history of severe allergic reactions to immunoglobulins -Evidence of hemolytic disease in the mother or newborn that is not due to Rh incompatibility

Special Precautions

-Monitor for signs of allergic reactions during and after administration -Use with caution in patients with a history of thrombocytopenia -Ensure correct blood type and Rh factor compatibility

Side Effects

-Fever -Chills -Headache -Rash -Allergic reactions (rare)

Drug Interactions

-May interact with live virus vaccines (e.g., measles, mumps, rubella) -Use caution with other blood products or immune globulins