N-Acetylcysteine
It is a commonly used as a mucolytic drug, and at higher doses it increases the cellular levels of reduced glutathione, an antioxidant, which influence insulin receptor activity. The NAC may exert the same effects at the ovarian level and thus can help in inducing ovulation. Its efficacy for ovulation is increased when it is combined with clomiphene and folic acid.Polycystic ovary syndrome and clomiphene-resistant infertility.
Oral, 1.6-3g/day, in three divided doses.
Hypersensitivity.
Asthmatics, peptic ulcer, lactation, pregnancy.
Stomatitis, nausea, vomiting, rhinorrhoea, drowsiness, chest tightness, bronchoconstriction
Nitroglycerine, Activated Charcol.
