Tinocordin

It exerts its action by promoting leucocytosis with predominant effect on neutrophils. It enhances phagocytic and intracellular killing capacity of macrophages and PMN's, stimulates release of cytokines like GM-CSF, IL1, IL2 and causes the proliferation of B-lymphocytes.

Indications

Adjuvant in chronic recurrent tonsillitis, peritonsillar abscess, chronic otitis media tuberculosis, chronic bronchitis, chronic recurrent allergic bronchial asthma, hepatitis B infections, cirrhosis of the liver, obstructive jaundice, peritonitis, post surgical abdominal infections in diabetes mellitus, burns, malicnancy and patients on cancer chemotherapy.

Dosage

-Adults: 500mg thrice daily for 2-4weeks. It may be given for upto 6 months in conditions like tuberculosis, malignancy and other recurrent infection. -Children : 100mg thrice daily.

Contra-Indications

-Hypersensitivity to Tinocordin or any of its components -Severe liver or kidney impairment -Pregnancy (unless clearly needed) -Breastfeeding (consult healthcare provider)

Special Precautions

-Monitor liver and kidney function regularly. -Use with caution in patients with a history of gastrointestinal disorders. -Not recommended for use in children without medical advice.

Side Effects

-Common: Nausea, headache, dizziness, rash. -Serious: Liver toxicity, severe allergic reactions, jaundice.

Drug Interactions

-Anticoagulants: May increase the risk of bleeding. -Antacids: Can reduce the absorption of Tinocordin. -Certain antibiotics: May interact and affect the efficacy of Tinocordin.