Voriconazole

It is a triazole antifungal agent.

Indications

Invasive aspergillosis, candidermia in nonneutropenic patients and the following Candida infections: disseminated infections in skin and infections in abdomen, kidney, bladder wall and wounds. Esophageal candidiasis, Serious fungal infections caused by Scedosporium apiospermum.

Dosage

Tablets or oral suspension should be taken at least one hour before or one hour following, a meal Voriconazole I.V. for injection requires reconstitution to 10mg/mL and subsequent dilution to 5mg/mL or less prior to administration as an infusion, at a maximum rate of 3mg/kg per hour over 1-2 hours. Voriconazole I.V. must not be infused concomitantly with any blood product or short-term infusion of concentrated electrolytes, even if the two infusions are running in separate intravenous lines (or

Side Effects

Visual disturbances, fever, rash, vomiting, nausea, diarrhea, headache, sepsis, peripheral edema, abdominal pain, and respiratory disorder.