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PRIDOXINE HYDROCHLORIDE

PRIDOXINE HYDROCHLORIDE

Pyridoxine Hydrochloride, also known as vitamin B6, is a water-soluble vitamin that is essential for numerous bodily functions. It is involved in protein, fat, and carbohydrate metabolism, the creation of neurotransmitters, and the production of red blood cells.

Indications

-Treatment of vitamin B6 deficiency -Management of sideroblastic anemia -Treatment of certain types of seizure disorders -Supplementation in patients receiving isoniazid or penicillamine -Prevention of drug-induced neuropathy


Dosage

-Adults: The typical daily dosage ranges from 1.3 to 2 mg. For therapeutic purposes, higher doses may be prescribed, typically between 50 to 200 mg per day. -Children: Dosage varies depending on age and condition, typically 0.5 to 2 mg per day. -Specific conditions: Dosages for specific conditions should be determined by a healthcare provider.


Contra-Indications

Hypersensitivity to Pyridoxine Hydrochloride or any component of the formulation


Special Precautions

-Use with caution in patients with renal impairment -Monitor for signs of peripheral neuropathy with long-term, high-dose use -Pregnant and breastfeeding women should consult a healthcare provider before use


Side Effects

-Nausea -Headache -Drowsiness -Paresthesia -Sensory neuropathy with prolonged use of high doses


Drug Interactions

-Reduces the efficacy of levodopa when used without a decarboxylase inhibitor -May decrease the plasma concentrations of certain antiepileptic drugs such as phenytoin and phenobarbital -Interaction with isoniazid and penicillamine, which may require increased dosages of Pyridoxine


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