Parkinsonism, drug induced extra-pyramidal symptoms, spasticity, closed cranio-cerebral trauma with concussion syndrome. Trigeminal neuralgia. Nicotine poisoning. Adjunct in Parkinsonism therapy.
Initially 2.5 mg thrice daily after meals increasing at intervals of 2-3 days by 2.5-5 mg daily. Usual max. : 30 mg daily. Not recommended for children.
Acute narrow angle glaucoma, urinary retention, tachycardia, paralytic ileus, prostatic hypertrophy.
Tendency to convulsion. recent M.I. concurrent admin. of C.N.S. depressants. Paediatrics: Not recommended. Pregnancy: Safety not clearly established. Lactation: Safety not clearly established. Elderly: Strict supervision and dosage monitoring.
Dryness of mouth, blurring of vision, headache, nausea, nervousness. Impairment of memory and organic confusional states, dizziness, constipation, delusions and hallucinations.
Tricyclic antidepressants, antiparkinsonism drugs, anti-histaminics, phenothiazines and quinidines have anticholinergic. Other oral drugs delays absorption.