Abiraterone
It is a CYP17 inhibitor indicated in combination with prednisone for the treatment of patients with metastatic castration-resistant prostate cancerOral; 1000mg once daily empty stomach along with prendisolone.
Pregnant female.
Paediatric: Safety and efficacy below 18 year not yet established. Pregnancy: Category X. Lactation: Not indicated. Elderly: Safe to use.
High blood pressure (hypertension), low blood potassium levels (hypokalemia), and fluid retention (edema),Dizziness, Headache, Confusion, Muscle weakness, Pain and swelling in legs.
Along with CYP3A4 inducer, rifampicin.