Adefovir

It belongs to new class of antiviral drugs called nucleotide analogues.

Indications

HBe-Ag positive and negative chronic hepatitis B, Lamivudine resistant HBV-HIV co-infection, Lamivudine resistant pre-transplant & post-transplant hepatitis B with decompensated liver disease.

Dosage

10mg per day.

Special Precautions

Symptoms of Hepatitis B may worsen if adefovir is stopped suddenly. Monitor kidney functions. Test for HIV before starting treatment with adefovir.

Side Effects

Pharyngitis, headache, asthenia, abdominal pain, flu like syndrome & nausea.