AMINACRINE HYDROCHLORIDE

Aminacrine Hydrochloride is a synthetic compound used primarily as an anti-inflammatory and antimalarial agent. It acts by inhibiting certain enzymes and processes in the body that contribute to inflammation and infection.

Indications

-Treatment of Malaria: Used in the management of malaria infections. -Anti-Inflammatory Therapy: Employed in conditions requiring anti-inflammatory treatment.

Dosage

-Adult Dosage: The typical dosage varies based on the condition being treated. For malaria, it might be administered in specific regimens prescribed by a healthcare provider. -Pediatric Dosage: Dosage for children is usually adjusted based on body weight and severity of the condition.

Contra-Indications

-Hypersensitivity: Contraindicated in individuals with known hypersensitivity to aminacrine or other acridine derivatives. -Pregnancy: Not recommended during pregnancy unless clearly needed.

Special Precautions

-Liver Function: Use with caution in patients with liver impairment. -Pregnancy and Lactation: Should be avoided unless deemed essential by a healthcare provider. -Renal Function: Caution is advised in patients with renal dysfunction.

Side Effects

-Common: Nausea, vomiting, and gastrointestinal disturbances. -Serious: Potential for severe allergic reactions, liver toxicity, and hematological issues.

Drug Interactions

-Anticoagulants: May increase the risk of bleeding when used with anticoagulants. -Other Antimalarials: Interaction with other antimalarial drugs could enhance or reduce efficacy.