Look for Drugs and Conditions



It is a quinoline derivative is a new antipsychotic agent with a unique pharmacological profile in that it is a partial agonist at the D2 and 5-HT1A receptor sites and an antagonist at the 5-HT2A receptor site.


Schizophrenia- acute treatment, Schizophrenia-chronic treatment, Acute mania.


The recommended starting and target dose for aripiprazole is 10 or 15 mg/day administered on a once-a-day schedule without regard to meals. Dosage increases should not be made before 2 weeks, the time needed to achieve steady state. At least 1 to 2 weeks, and sometimes up to 4 weeks, may pass before aripiprazole reaches its full effects.



Special Precautions

Aripiprazole should be used with caution in patients with known cardiovascular diseases (history of myocardial infarction or ischemic heart disease, heart failure or conduction abnormalities, cerebrovascular diseases, or conditions, which would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications), Alzheimer's disease, and dementia.

Side Effects

Headache, insomnia, somnolence, dyspepsia, constipation, pain, nausea, vomiting, asthenia, dizziness, abdominal pain, dry mouth, anxiety, akathisia, orthostatic, hypotension, hypertonia, tremor, blurred vision.

Ad 5