ATROPINE

Atropine is an alkaloid derived from the plant Atropa belladonna and is classified as an anticholinergic drug. It acts as a muscarinic antagonist and is used to treat muscarinic overdose.

Indications

Bronchospasm, peptic ulcer, bradycardia, muscarinic poisoning, cholinergic drug overdose, mushroom poisoning, organophosphate toxicity, carbamate toxicity, uterine contraction, ocular inflammation, and parkinsonism.

Dosage

An average dose when atropine injection is used for antivagal action is 0.6-1 mg ( 5-10 ml of 0.1mg/ml solution), to treat muscarinic overdose 2mg to 3mg ( 20-30 ml of 0.1mg/ml solution ), to treat bradycardia 1-2mg (3 mag is maximum dose) And for pediatric purposes 0.01-0.02 mg/kg ( children more than 5 kg ).

Contra-Indications

Hepatic impairment and renal impairment.

Special Precautions

Consult a Physician before using it during pregnancy and breastfeeding.

Side Effects

Dry mouth, blurred vision, lack of seating, vomiting, dizziness, hypersensitivity reaction, palpitation, tachycardia ( fast heartbeat), urine retention, glaucoma, lightheadedness, muscle stiffness, fever, slurred speech, and difficulty in breathing.

Drug Interactions

Antihistamine drugs, tricyclic antidepressant drugs, metoclopramide, domperidone, and disopyramide.