Avanafil

Avanafil is a phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED) in men. It works by increasing blood flow to the penis during sexual stimulation, helping to achieve and maintain an erection.

Indications

Erectile Dysfunction (ED)

Dosage

-Initial Dose: 100 mg taken orally approximately 15-30 minutes before sexual activity. -Maintenance Dose: Adjusted to 50 mg or increased to 200 mg based on efficacy and tolerability. -Maximum Frequency: Once per day.

Contra-Indications

Known hypersensitivity to Avanafil or any of its components. -Concurrent use with nitrates or nitric oxide donors. -Severe cardiovascular conditions or recent stroke/heart attack. -Severe hepatic or renal impairment.

Special Precautions

-Use with caution in patients with cardiovascular disease. -Avoid use in patients predisposed to priapism or with anatomical deformation of the penis. -Not recommended for use in women, children, or adolescents.

Side Effects

-Common: Headache, flushing, nasal congestion, and dizziness. -Rare: Vision changes, back pain, and prolonged erection (priapism). -Seek medical attention for serious allergic reactions or chest pain.

Drug Interactions

-Increased hypotensive effect with nitrates or alpha-blockers. -Potential interactions with CYP3A4 inhibitors such as ketoconazole and ritonavir. -Avoid alcohol as it may enhance side effects.