Besifloxacin

-Besifloxacin is an ophthalmic fluoroquinolone antibiotic used to treat bacterial eye infections. It belongs to the class of drugs known as fluoroquinolones, which work by inhibiting bacterial DNA synthesis. -Besifloxacin ophthalmic suspension is a quinolone antimicrobial, used in eye infection.

Indications

-Besifloxacin is indicated for the treatment of bacterial conjunctivitis, a common eye infection caused by susceptible strains of bacteria. -Ophthalmic bacterial infection indicated for the treatment of conjunctivitis caused by susceptible isolates of the following bacteria: Aerococcus viridans , CDC coryneform group G, Corynebacterium pseudodiphtheriticum, Corynebacterium striatum, Haemophilus influenzae, Moraxella catarrhalis, Moraxella lacunata, Pseudomonas aeruginosa , Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus hominis, Staphylococcus lugdunensis, Staphylococcus warneri, Streptococcus mitis group, Streptococcus oralis, Streptococcus pneumoniae, Streptococcus salivarius.

Dosage

-The recommended dosage for besifloxacin is typically one drop in the affected eye(s) three times a day for seven days, or as directed by a healthcare professional. Follow the prescribed regimen and complete the full course of treatment. -Topical; 6mg/ml (0.6%) Instill one drop in the affected eye(s) 3 times a day, 4 to 12 hours apart for 7 days.

Contra-Indications

Besifloxacin is contraindicated in individuals with a known hypersensitivity to besifloxacin or any other components of the formulation.

Special Precautions

-Contact lenses should be removed before instilling besifloxacin eye drops and may be reinserted 15 minutes after administration. -Avoid contaminating the applicator tip, as this may lead to infection. If there is no improvement in symptoms after a few days of treatment, consult a healthcare professional. -Paediatric: Safety and efficacy of in pediatric patients of less than 1 years have not been established. Pregnancy: Data no sufficient, however systemic exposure to besifloxacin from ocular administration is low. Lactation: Data no sufficient, however systemic exposure to besifloxacin from ocular administration is low. Elderly: Data not sufficient.

Side Effects

-Common side effects may include eye irritation, itching, redness, and discomfort. If any unusual or severe side effects occur, seek medical attention promptly. -Redness, blurred vision, eye pain, eye irritation, eye pruritus and headache.

Drug Interactions

There are no significant drug interactions reported with besifloxacin. However, it is essential to inform your healthcare provider about all medications, including over-the-counter drugs and supplements, that you are taking.