Beta Cyclodextrin

Beta Cyclodextrin is a cyclic oligosaccharide composed of seven glucose units. It is used to enhance the solubility and stability of various drugs, improving their bioavailability. It forms inclusion complexes with hydrophobic compounds, aiding in the delivery and effectiveness of pharmaceutical products.

Indications

-Enhances solubility and stability of poorly water-soluble drugs -Improves the oral bioavailability of various medications -Used in formulations for controlled-release drug delivery systems

Dosage

Dosage varies based on the specific drug being formulated and the intended use. It is typically used in concentrations ranging from 1% to 10% of the total formulation. The exact dosage should be determined based on the formulation requirements and the drug's specific needs.

Contra-Indications

-Known hypersensitivity to Beta Cyclodextrin -Use with caution in patients with renal impairment, as high doses may affect kidney function.

Special Precautions

-Monitor renal function in patients receiving high doses or prolonged use. -Ensure compatibility with other ingredients in drug formulations to avoid adverse reactions.

Side Effects

-Generally well-tolerated; however, excessive use may lead to gastrointestinal disturbances such as nausea or diarrhea. -Allergic reactions are rare but possible.

Drug Interactions

May interact with certain drugs by altering their absorption or release rates. It is essential to evaluate the compatibility of Beta Cyclodextrin with other active ingredients in the formulation.