Betaxolol

It is a selective (b1-adrenergic) receptor blocking agent when instilled in the eye reduces elevated as well as normal intraocular pressure, whether or not accompained by glaucoma. It does not have significant membrane stabilising (local anaesthetic) activity and is devoid of intrinsic sympathomimetic action.

Indications

Ocular hypertension and chronic open angle glaucoma.

Dosage

1drop instilled in the affected eye(s)twice daily.

Contra-Indications

Sinus bradycardia greater than a first degree atrioventricular block, cardiogenic shock or a histroy of overt cardiac failure and in patients with hypersensitivity.

Special Precautions

Not for injection. Diabetes, thyrotoxicosis. History of obstructive pulmonary disease, cardiac failure. Potential additive effect if given with oral b-adrenergic blocking agent. It should be used with a miotic to reduce elevated intra ocular pressure in angle - closure glaucoma. Pregnant & lactating women, children.

Side Effects

Decreased corneal sensitivity, erythema, itching, corneal punctate staining keratitis, anisocoria & photophobia.

Drug Interactions

Enhances calcium channel blockers, anaesthetics and clonidine.