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Brimonidine Tartrate

Brimonidine Tartrate

brimonidine tartrate is an alpha adrenergic receptor agonist with high degree of selectivity to alpha2 receptors. It has a peak ocular hypotensive effect occurring at two hours post-dosing.


brimonidine tartrate is indicated for lowering intraocular pressure in patients with open angle glaucoma or ocular hypertension.


One drop in the affected eye(s).


Hypersensitivity , (MAO) inhibitor therapy.

Special Precautions

Severe cardiovascular disease.Hepatic and renal impairment, depression, cerebral and coronary insufficiency, Raynaud’s phenomenon, orthostatic hypotension or thromboangitis obliterans. Pregnancy: brimonidine tartrate should be used cautioushs during pregnancy. Nursing Mothers : It is not known whether brimonidine tartrate is excreted in human milk, although in animal studies, brimonidine tartrate has been shown to be excreted in breast milk. Paediatric use : Safety and effectiveness

Side Effects

Oral dryness, ocular hyperemia, burning and stinging, headache, blurring, foreign bodies sensation, fatigue/drowsiness, conjunctival follicles, ocular allergic reactions and ocular pruritis.

Drug Interactions

Beta blockers (ophthalmic and systemic), antihypertensives and/or cardiac glycosides, tricyclic anti depressants.

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