Carboxymethylcellulose

Carboxymethylcellulose (CMC) is a derivative of cellulose, a natural polymer found in plant cell walls. It is commonly used as a thickening agent and stabilizer in various pharmaceutical and food products. CMC is highly soluble in water and forms a viscous gel-like substance when dissolved, making it useful in formulations where viscosity and consistency need to be controlled.

Indications

CMC is used in medicine primarily as an ingredient in eye drops and artificial tears to relieve dryness and irritation of the eyes. It acts as a lubricant and hydrating agent on the surface of the eye, providing temporary relief from symptoms of dry eye syndrome.

Dosage

The dosage of carboxymethylcellulose in eye drops varies depending on the specific formulation and severity of dry eye symptoms. Typically, one to two drops are instilled into the affected eye(s) as needed, up to several times daily.

Contra-Indications

Individuals with a known allergy or hypersensitivity to carboxymethylcellulose or any of its components should avoid using products containing this substance.

Special Precautions

Caution should be exercised when using carboxymethylcellulose in patients wearing contact lenses, as certain formulations may contain preservatives that can accumulate on the lenses. It is advisable to remove contact lenses before applying eye drops and wait at least 15 minutes before reinserting them.

Side Effects

Common side-effects associated with carboxymethylcellulose eye drops include temporary stinging or burning sensation upon application. Rarely, allergic reactions such as redness, swelling, or itching of the eye(s) may occur. If these symptoms persist or worsen, medical attention should be sought promptly.

Drug Interactions

There are no known significant drug interactions with carboxymethylcellulose eye drops.