Carnitine

Carnitine is a naturally occurring amino acid derivative that plays a crucial role in the production of energy by transporting fatty acids into your cells' mitochondria, which act as engines within your cells, burning these fats to create usable energy. Carnitine supplements are often used to support weight loss, enhance athletic performance, and improve heart health.

Indications

-Management of primary and secondary carnitine deficiency -Support for patients undergoing hemodialysis -Improvement of exercise performance and recovery -Potential aid in weight loss programs -Adjunctive treatment in certain heart conditions such as angina and heart failure

Dosage

-Adults: 1-3 grams per day, divided into several doses -Children: Dosage based on body weight, usually 50-100 mg/kg/day, divided into 2-3 doses

Contra-Indications

-Known hypersensitivity to carnitine or any component of the formulation -Patients with severe renal impairment without proper medical supervision

Special Precautions

-Use with caution in patients with a history of seizure disorders, as carnitine may increase the risk of seizures -Monitor blood levels in patients with renal impairment -Pregnant and breastfeeding women should consult a healthcare professional before use

Side Effects

-Mild gastrointestinal symptoms (nausea, vomiting, stomach cramps) -Diarrhea -Fishy body odor -Rarely, seizures in patients predisposed to seizure disorders

Drug Interactions

-May interact with anticoagulants like warfarin, potentially altering their effects -Potential interaction with thyroid hormone replacement therapy -Concurrent use with certain antibiotics may affect carnitine levels