Ceftriaxone with Vancomycin

Indications

It is indicated in the following infections due to susceptible organisms. Pneumonia (Ventilated Associated Pneumonia, Hospital acquired Pneumonia, Bacterial Meningitis, Bacterial Endocarditis, Septicemia, Infections in immunocompromised patients.

Dosage

Adjustment in Renal Impairment: Ceftiraxone is excreted via both biliary and renal excretion. Therefore, patients with renal failure normally require no adjustment in dosage when usual doses of ceftriaxone are administered. Dosage adjustment with vancomycin must be made in patients with impaired renal function. There are no dosage reduction studies for the combination in renal impairment.