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Celexocib is is a nonsteroidal antiinflammatory drug selective cyclooxygenase (COX-2) inhibitor.


It indicated for Osteoarthritis (OA) , Rheumatoid Arthritis (RA), Juvenile Rheumatoid Arthritis (JRA) in patients 2 years and older, Ankylosing Spondylitis (AS), Acute Pain, Primary Dysmenorrhea (PD)


Oral; 50,100,200,400 mg: Use the lowest effective dosage for the shortest duration consistent with individual patient treatment goals • OA: 200 mg once daily or 100 mg twice daily • RA: 100 to 200 mg twice daily • JRA: 50 mg twice daily in patients 10-25 kg. 100 mg twice daily in patients more than 25 kg • AS: 200 mg once daily single dose or 100 mg twice daily. If no effect is observed after 6 weeks, a trial of 400 mg (single or divided doses) may be of benefit. • PD: 400 mg initially, followed by 200 mg dose if needed on first day. On subsequent days, 200 mg twice daily as needed.


Known hypersensitivity to celecoxib, or any components of the drug product or sulfonamides, History of asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs, In the setting of CABG surgery

Special Precautions

Hepatic Impairment: Reduce daily dose by 50% in patients with moderate hepatic impairment (Child-Pugh Class B).

Side Effects

Common side effects may include: -Gastrointestinal discomfort -Headache -Dizziness -Edema -Hypertension Serious side effects may include: -Cardiovascular events -Gastrointestinal bleeding -Renal impairment

Drug Interactions

Celecoxib may interact with: -Anticoagulants (e.g., warfarin) Antiplatelet drugs (e.g., aspirin) -ACE inhibitors -Diuretics -Lithium Consultation with a healthcare professional is advised when combining celecoxib with other medications.

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