Celiprolol

Celiprolol is indicated for the management of mild to moderate hypertension and effort-induced angina pectoris.

Indications

Hypertension, Angina pectoris.

Dosage

Adults : 200-400mg once daily.

Contra-Indications

Hypersensitivity, sinus bradycardia, >1st degree heart block, cardiogenic shock, uncompensated heart failure, hypotensive patients. Pregnancy (2nd & 3rd trimesters).

Special Precautions

Asthma, lactation.

Side Effects

Nausea, diarrhoea, abdominal discomfort, headache, fatigue, dizziness, insomnia.

Drug Interactions

May exacerbate rebound HTN upon withdrawal of clonidine. May increase AV conduction time w/ digitalis glycosides. Reduced bioavailability w/ concomitant hydrochlorothiazide, chlorthalidone or theophylline. Concomitant dihydropyridine Ca channel blockers (e.g. nifedipine) may increase the risk of hypotension and heart failure.