Chlorbutol

Chlorbutol, also known as Chlorobutanol, is a white, crystalline, camphor-like odorant substance used as a preservative and antiseptic in pharmaceutical formulations. It possesses bacteriostatic and fungistatic properties, making it suitable for use in ophthalmic and otic preparations.

Indications

-Preservative in eye drops and ear drops -Antiseptic for minor cuts and wounds -Component in topical anesthetic creams and ointments

Dosage

-Ophthalmic solutions: Typically, concentrations range from 0.5% to 1% -Otic solutions: Concentrations usually range from 0.5% to 1% -Topical preparations: Used as per the product formulation guidelines

Contra-Indications

-Hypersensitivity to Chlorbutol or any component of the formulation -Not to be used in patients with severe ocular or otic infections

Special Precautions

-Use with caution in patients with known allergies -Avoid prolonged use to prevent irritation or sensitization -Do not apply to deep or puncture wounds, animal bites, or serious burns

Side Effects

-Local irritation or sensitization at the site of application -Allergic reactions such as itching, redness, or swelling -Rarely, systemic side effects if absorbed in significant amounts

Drug Interactions

No significant drug interactions reported, but always consult with a healthcare provider before combining with other medications