Deflazacort

Deflazacort is a glucocorticoid used primarily as an anti-inflammatory and immunosuppressant medication.

Indications

Rheumatoid Arthritis & Juvenile Chronic Arthritis, Asthma and other airway diseases, Pemphigus, Uveitis, Nephrotic Syndrome, Immunne suppression in transplantation.

Dosage

The dosage of Deflazacort varies depending on the condition being treated and should be determined by a healthcare provider. It is usually administered orally.

Contra-Indications

Hypersensitivity. Patients receiving live virus immunisation.

Special Precautions

Special precautions should be taken in patients with diabetes, hypertension, osteoporosis, and those receiving immunosuppressive therapy. Long-term use may require monitoring for potential adverse effects.

Side Effects

Common side effects of Deflazacort include weight gain, fluid retention, increased appetite, mood changes, and gastrointestinal disturbances. Long-term use may lead to osteoporosis and increased susceptibility to infections.

Drug Interactions

-Strong CYP3A4 inhibitors and inducers, affecting drug plasma levels. -Nonsteroidal anti-inflammatory drugs (NSAIDs), which may increase the risk of gastrointestinal ulcers. - Immunosuppressants, such as cyclosporine, which may potentiate their effects.