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DEXAMETHASONE

DEXAMETHASONE

Very potent and highly selective glucocorticoid. Long acting. Causes marked, pituitary-adrenal suppression, but fluid retention and hypertension are not a problem. It meets any emergency with intensified potency and strikingly rapid corticosteroid action, thus ensuring speedy reversal of the situation in the patients favour.

Indications

Allergic reactions, pre & post-operatively. Acute stage of infections, poisoning, adrenocortical insufficiency, shock, acute dermatological disorders, rheumatic disorders, ophthalmologic disorders.


Dosage

4-20 mg/day i.v. infusion or i.m. 0.5-5 mg/day orally.


Contra-Indications

Renal failure, diabetes mellitus, psychosis, osteoporosis. Pregnancy. CHF, tuberculosis & other systemic infections.


Special Precautions

May reduce the response of the pituitary-adrenal axis to stress. Glaucoma, epilepsy, hypertension. Liver dysfunction. Elderly.


Side Effects

Cushing’s habitus (rounded face, narrow mout). Fragile skin, easy bruising, tele- ngiectasis, hirsutism. Cutaneous atrophy occurs with topical use. Hyperglycaemia, glycosuria, muscular weakness. Delayed healing of wounds & surgical incisions.


Drug Interactions

Phenytoin, phenobarb, ephedrine and rifampicin reduce efficacy G.I. absorption reduced by magnesium trisilicate. Salicylates efficacy reduced.


Other Combination Brands
Brand Name Manufactured by
AMOFLOX-D Kaizen Drugs
ANCHLOR DX NRI VISION CARE
AUTO RELIEF PRG PHARMA PVT. LTD.
BRUDEX PRG PHARMA PVT. LTD.
BSTQUIN-D I Q MED HEALTHCARE
CENTREX-PD ALTREX
CEPROLEN-D INDOCO REMEDIES LTD.
CIPODEX UNICURE (INDIA) PVT. LTD.
DECHOL OYSTER LABS LIMITED
DECOL-C INTAS PHARMACEUTICALS LTD.
DEXAFEN UNICURE (INDIA) PVT. LTD.
DEXAGEN UNICURE (INDIA) PVT. LTD.
DEXORAM PAREX PHARMACEUTICALS PVT.
DEXORAM-P PAREX PHARMACEUTICALS PVT.
EYEMIX-D SOLITAIRE BIOTECH PVT. LTD.
EYLOX-D SOLITAIRE BIOTECH PVT. LTD.
EYMIX-C SOLITAIRE BIOTECH PVT. LTD.
FLAN-DX PHARMTAK OPHTALMICS PVT. LTD.
FLOMED-D ALOMED FORMULATIONS PVT. LTD.
FORFLOXACIN-D FORTUNE LABS
FULDEX-O PLATINUM PHARMA
FULMAX-D PLATINUM PHARMA
GENIAL-D CYTOCHEM HEALTHCARE (INDIA) PVT. LTD.
K-MOXI-D Kaizen Drugs
KEDEX OPTICA PHARMACEUTICALS
KITMOX DX SENTISS PHARMA
LEEDEXA JOHNLEE PHARMACEUTICALS PVT LTD
LOXIN-DX ALEXIN OPTHALMICS
MICROFLOX-DX MICROVISION
MOXI 4G DX Mediqas Pharma pvt. Ltd.
MOXIFOX-DX MARXX PHARMA
MOXIL-D SOLARIUM HEALTHCARE
MOXINEX-D (Tray Pack) INDKUS BIOTECH INDIA
MOXISET DX AMWIN PHARMA PVT LTD
MOXITA-DM Aryca Pharmaceuticals
MOXZON-DX ANEXAS PHARMACEUTICALS
MYTICOM ALLERGAN INDIA LTD.
OFELDER-D ELDER PHARMACEUTICALS LTD.
OFRYCA-DM Aryca Pharmaceuticals
POLYDEX VSD LIFESCIENCES
PROXO-D PROHEALTH VITAMINS (P) LTD.
PYRICORT FDC LTD.
PYRIMON FDC LTD.
SCAT-DM LE SANTE
SETOFF-D Rax Health Care Pvt. Ltd.
TAKCHLOR-C PHARMTAK OPHTALMICS PVT. LTD.
TAKCHLOR-C PHARMTAK OPHTALMICS PVT. LTD.
TRUOF - D AROMA LIFE SCIENCE
ULTRAFLOX-D ULTRATECH PHARMACEUTICALS
UNICIPAX-DX UNIVERSAL PHARMA
UNIPYROL UNIVERSAL PHARMA
ZOXAN-D FDC LTD.
ZYCIN-DX MEDICON OPHTHALMICS
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