Dextromethorphan and Guaifenesin

Dextromethorphan Guaifenesin is a combination medication used to relieve cough and chest congestion. Dextromethorphan is a cough suppressant that affects the signals in the brain that trigger the cough reflex. Guaifenesin is an expectorant that helps loosen congestion in the chest and throat, making it easier to cough out through the mouth.

Indications

-Relief of cough associated with the common cold, bronchitis, and other respiratory illnesses. -Alleviation of chest congestion due to mucus buildup.

Dosage

-Adults and children 12 years and older: Typically, 10 ml every 4 hours. Maximum of 6 doses in 24 hours. -Children 6 to 12 years: 5 ml every 4 hours. Maximum of 6 doses in 24 hours. -Children under 6 years: Consult a physician before use.

Contra-Indications

-Hypersensitivity to dextromethorphan, guaifenesin, or any component of the formulation. -Use in patients taking monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping MAOIs.

Special Precautions

-Consult with a healthcare provider if you have a persistent cough due to smoking, asthma, chronic bronchitis, or emphysema. -Use with caution in patients with a history of drug abuse or substance use disorder. -Not recommended for use in children under 6 years of age without medical advice. -Pregnant and breastfeeding women should seek medical advice before use.

Side Effects

-Drowsiness -Dizziness -Nausea -Vomiting -Upset stomach -Headache -Rash (rare)

Drug Interactions

-Avoid using with other medications that also contain dextromethorphan or guaifenesin. -Increased risk of serotonin syndrome when taken with other serotonergic drugs (e.g., SSRIs, SNRIs, tricyclic antidepressants). -Potential interaction with alcohol and other central nervous system depressants.