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DICLOFENAC POTASSIUM WITH SERRATIOPEPTIDASE

DICLOFENAC POTASSIUM WITH SERRATIOPEPTIDASE

Diclofenac potassium with serratiopeptidase is a combination medication that contains diclofenac potassium, a nonsteroidal anti-inflammatory drug (NSAID), and serratiopeptidase, an enzyme with anti-inflammatory properties. Diclofenac works by reducing inflammation and pain, while serratiopeptidase aids in the breakdown of proteins, contributing to its anti-inflammatory effects.

Indications

This combination is commonly prescribed for the treatment of inflammatory conditions associated with pain and swelling, such as rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and acute musculoskeletal injuries.


Dosage

The dosage may vary based on the specific condition being treated and individual patient factors. It is crucial to follow the prescribed dosage and administration instructions provided by the healthcare professional.


Contra-Indications

This medication is contraindicated in individuals with a history of hypersensitivity to diclofenac, serratiopeptidase, or other NSAIDs. Contraindications also include patients with a history of gastrointestinal bleeding, peptic ulcers, severe renal or hepatic impairment, and during the third trimester of pregnancy.


Special Precautions

-Caution is advised in patients with a history of cardiovascular diseases, as NSAIDs may increase the risk of serious cardiovascular events. -Monitoring renal function is essential, especially in patients with pre-existing renal conditions. -Elderly patients are more susceptible to adverse effects, and lower doses may be recommended. -Avoid concurrent use with other NSAIDs or anticoagulants to reduce the risk of bleeding.


Side Effects

Common side effects may include gastrointestinal discomfort, nausea, headache, dizziness, and skin rash. Serious side effects like gastrointestinal bleeding, cardiovascular events, and allergic reactions are rare but possible.


Drug Interactions

Interactions may occur with anticoagulants, antiplatelet drugs, ACE inhibitors, diuretics, and other NSAIDs. Combining this medication with other drugs affecting the gastrointestinal tract or renal function requires careful monitoring.


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