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Dicyclomine

Dicyclomine

Orally has direct smooth muscle relaxant action in addition to weak anticholinergic effects thereby being used as an antispasmodic agent.

Indications

G.I. spasm. Irritable bowel syndrome. Hyperperistalsis, peptic ulcer, functional diarrhoea.


Dosage

Adults: Oral: 20 mg, 3-4 times daily. Parenteral: 20 mg I.M. 4-6 hourly as required. Children: Suspn: 2.5-5 ml 2-3 times per day. Parenteral: 10 mg I.M. 4-6 hourly up to 40 mg per day.


Contra-Indications

Dicyclomine is contraindicated in individuals with a known hypersensitivity to the drug, as well as in patients with glaucoma, obstructive uropathy, paralytic ileus, severe ulcerative colitis, and myasthenia gravis.


Special Precautions

Prostatic hypertrophy. Suspected glaucoma. Paediatrics: Reduced dose necessary. Age. Elderly: No special problems.


Side Effects

Common side effects of dicyclomine may include dry mouth, blurred vision, dizziness, drowsiness, constipation, difficulty urinating, and increased sensitivity to light. Rare but serious side effects may include hallucinations, confusion, agitation, and allergic reactions. Patients should seek medical attention if they experience any severe or persistent side effects.


Drug Interactions

Dicyclomine may interact with other medications, including but not limited to anticholinergic drugs, antihistamines, tricyclic antidepressants, and monoamine oxidase inhibitors (MAOIs). Patients should inform their healthcare provider about all medications, supplements, and herbal products they are taking before starting dicyclomine therapy.


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