Disodium EDTA
Disodium EDTA (Ethylenediaminetetraacetic acid disodium salt) is a chelating agent used in various pharmaceutical, cosmetic, and food products. It acts as a preservative and stabilizer by binding to metal ions, thereby preventing oxidation and degradation of products.Disodium EDTA is indicated for use as a chelating agent in pharmaceutical formulations, topical creams, ointments, and solutions. It is commonly used in eye drops, nasal sprays, and skincare products to enhance stability and shelf-life.
The dosage of Disodium EDTA varies depending on the formulation and intended use. It is typically included in products at concentrations ranging from 0.1% to 0.5%. Specific dosage instructions should be followed as directed by a healthcare professional or as indicated on the product label.
Disodium EDTA is generally considered safe for use in topical and ophthalmic formulations when used as directed. However, individuals with known hypersensitivity to EDTA or any component of the formulation should avoid its use.
Caution should be exercised when using Disodium EDTA in individuals with impaired renal function, as excessive accumulation of EDTA may occur. Prolonged or excessive use of products containing Disodium EDTA may lead to skin irritation or sensitization. Avoid contact with eyes and mucous membranes. If irritation occurs, discontinue use and consult a healthcare professional.
Side effects associated with Disodium EDTA are rare but may include skin irritation, allergic reactions, and contact dermatitis. Ingestion or inhalation of large quantities of Disodium EDTA may cause gastrointestinal discomfort or respiratory irritation.
Disodium EDTA may interact with certain medications, particularly those containing metal ions such as calcium, magnesium, iron, or zinc. It may decrease the effectiveness of some medications or alter their absorption. Patients should consult their healthcare provider before using Disodium EDTA-containing products concurrently with other medications.
