Look for Drugs and Conditions




Raised intra-ocular pressure in ocular hypertension, open-angle glaucoma, psuedoexfoliative glaucoma either as adjunct to beta-blocker or used alone in patients unresponsive to beta-blockers or if beta-blockers are contraindicated.


Used alone apply three times a day; if used with topical beta-blocker, apply twice daily.


Severe renal impairment or hyperchloraemic acidosis. Pregnancy, breast feeding.

Special Precautions

Hepatic impairments, systemic absorption following topical administration; history of renal calculi, chronic corneal defects, history of intraocular surgery.

Side Effects

Headache, dizziness, paresthesia, sinusitis, rhinitis, nausea, asthenia, hypersensitivity reactions, ocular burning, stinging and itching, blurred vision, lacrimation, conjunctivitis.

Drug Interactions

Similar to diuretics (carbonic anhydrase inhibitor)- as possibility of systemic absorption after topical administration.

Ad 5