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Dorzolamide

Dorzolamide

Dorzolamide is a carbonic anhydrase inhibitor used in the form of eye drops to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension.

Indications

Treatment of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension.


Dosage

Typically, one drop of Dorzolamide 2% eye drops is instilled into the affected eye(s) three times daily. Dosage may vary; follow healthcare provider's instructions.


Contra-Indications

Severe renal impairment or hyperchloraemic acidosis. Pregnancy, breast feeding.


Special Precautions

Hepatic impairments, systemic absorption following topical administration; history of renal calculi, chronic corneal defects, history of intraocular surgery.


Side Effects

Headache, dizziness, paresthesia, sinusitis, rhinitis, nausea, asthenia, hypersensitivity reactions, ocular burning, stinging and itching, blurred vision, lacrimation, conjunctivitis.


Drug Interactions

Similar to diuretics (carbonic anhydrase inhibitor)- as possibility of systemic absorption after topical administration.


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