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Dutasteride

Dutasteride

It is in a class of medications called 5-alpha reductase inhibitors. It works by blocking the production of a natural substance that enlarges the prostate.

Indications

Enlarged prostate (Benign prostatic hyperplasia - BPH).


Dosage

Adult : One capsule of 0.5mg orally once a day with or without food around the same time every day.


Contra-Indications

Hypersensitivity to dutastride and/or finasteride, liver disease or history of; prostate cancer.


Special Precautions

Use only in men; should not donate blood while taking dutasteride and for 6-months after stop taking it, donot drink grape juice, swallow the capsule whole, do not split, chew or crush it, do not take a double dose to make up for a missed one. Paediatric : Keep out of reach of children. Pregnancy: Pregnant women should not handle dutasteride capsule, touching the contents of capsule may harm fetus.


Side Effects

Decrease in sex drive, difficulty ejaculating, breast tenderness or enlargement.


Drug Interactions

Nutritional supplements, herbal products,antifungal-Fluconazole, itraconazole and ketoconazole, cimetidine, ciprofloxacin, clarithromycin, cyclosporine, danazol, delavirdine, dilitazem, erythromycin, fluoxetine, fluvoxamine, protease inhibiotors - indinavir and ritonavir, isoniazid, metronidazole, nefazodone, troleandomycin, verapamil, and zafirlukast.


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