Dutasteride with Silodosin
Dutasteride and Silodosin are medications used in combination to treat symptoms of benign prostatic hyperplasia (BPH), a condition characterized by an enlarged prostate gland. Dutasteride belongs to the class of 5-alpha-reductase inhibitors, while Silodosin is an alpha-blocker. The combination of these medications works synergistically to relieve BPH symptoms by reducing prostate size and improving urinary flow.The combination of Dutasteride with Silodosin is indicated for the treatment of signs and symptoms of benign prostatic hyperplasia (BPH) in adult men with an enlarged prostate.
The recommended dosage may vary, and it is essential to follow the healthcare provider's prescription. Typically, a common dosage is one Dutasteride 0.5 mg capsule daily, alongside one Silodosin 8 mg capsule daily. The capsules should be taken orally with water and can be taken with or without food.
This medication combination is contraindicated in individuals with a known hypersensitivity to Dutasteride, Silodosin, or any of the components in the formulation. It is also contraindicated in women and children.
-Caution should be exercised in patients with a history of orthostatic hypotension. -Patients should be monitored for signs of prostate-specific antigen (PSA) levels during treatment. -Dutasteride with Silodosin may cause dizziness, and patients should avoid activities requiring mental alertness until they know how the medication affects them.
Common side effects may include dizziness, decreased libido, erectile dysfunction, and retrograde ejaculation. Contact a healthcare professional if any unusual or severe side effects occur.
Dutasteride with Silodosin may interact with medications affecting the CYP3A4 enzyme system. Careful monitoring is recommended when used concomitantly with potent CYP3A4 inhibitors or inducers.
