EDTA

EDTA is a chelating agent that binds to metal ions, facilitating their removal from the body. It is commonly used in medical treatments to manage heavy metal poisoning and in laboratory settings for various analytical purposes.

Indications

-Heavy metal poisoning (e.g., lead, mercury) -Hypercalcemia (high calcium levels) -Certain types of kidney stones -Testing for heavy metal levels in blood

Dosage

-For Lead Poisoning: Typically administered intravenously. Dosage is adjusted based on the patient's condition and weight. -For Hypercalcemia: Dosage and administration are individualized, often administered via intravenous infusion. -For Laboratory Use: EDTA is added to blood samples in a specific concentration to prevent clotting.

Contra-Indications

-Known hypersensitivity to EDTA -Severe renal impairment -Active bleeding conditions

Special Precautions

-Monitor renal function during treatment, especially in patients with pre-existing kidney issues. -Avoid using in patients with severe heart disease. -Ensure proper hydration to minimize the risk of kidney damage.

Side Effects

-Nausea and vomiting -Diarrhea -Headaches -Fever -Rarely, severe renal impairment or hypocalcemia

Drug Interactions

-May interact with other chelating agents or anticoagulants. -Monitor calcium levels if used with calcium supplements. -Caution when used with drugs affecting kidney function.