Eflornithine Hydrochloride
Eflornithine Hydrochloride is a medication used primarily for the treatment of African sleeping sickness (Trypanosomiasis), particularly the second stage of the disease caused by Trypanosoma brucei gambiense. It works by inhibiting an enzyme essential for the growth of the parasite.African Sleeping Sickness (Stage II): Effective against Trypanosoma brucei gambiense infections.
-Adults: Typically administered as an intravenous infusion. Dosage and duration of treatment should be determined by a healthcare provider based on the severity of the infection and the patient’s overall health. -Children: Dosage may vary based on age and weight; consult a healthcare provider for precise dosing.
-Hypersensitivity: Contraindicated in patients with known hypersensitivity to Eflornithine Hydrochloride or any of its excipients. -Pregnancy: Should be used during pregnancy only if clearly needed, as safety during pregnancy is not well established.
-Renal Impairment: Use with caution in patients with renal impairment. Dosage adjustments may be necessary. -Hepatic Impairment: Caution is advised in patients with liver disease.
-Common: Diarrhea, nausea, abdominal pain, and headache. -Severe: Fever, rash, and allergic reactions. Immediate medical attention is required if severe side effects occur.
Drug Interactions: Potential interactions with other medications should be evaluated. Inform your healthcare provider about all other medications being taken, including over-the-counter drugs and supplements.
