ELETRIPTAN HBR

Indications

Acute attack of migraine

Dosage

Adult 18-65 yr Initially 40 mg, repeated if necessary after 2 hr. Max: 160 mg/day.

Contra-Indications

Severe hepatic or renal impairment, uncontrolled HTN, confirmed CHD including ischaemic heart disease peripheral vascular disease. History of CVA or transient ischaemic attack. Concomitant ergotamine, ergotamine derivatives (including methysergide), other 5-HT1 receptor agonists.

Special Precautions

Not to be used in hemiplegic or basilar migraine.Elderly, renal impairement, pregnancy, lactation and children. Use in caution in drivers or machine operators.

Side Effects

Fatigue, somnolence, dizziness, nausea.

Drug Interactions

Erythromycin, ketoconazole, specific & potent CYP3A4 inhibitors eg itraconazole & clarithromycin.