ESTRADIOL VALERATE

Estradiol Valerate is a form of estrogen, a female sex hormone that is essential for the regulation of the menstrual cycle and reproductive system in women. It is used as a hormone replacement therapy in menopausal women to relieve symptoms such as hot flashes, vaginal dryness, and other signs of estrogen deficiency.

Indications

Climacteric complaints after the cessation of monthly bleeding, or deficiency symptoms after oophorectomy or radiological castration for non-carcinomatous diseases, such as hot flushes, outbreaks of sweat, sleep disturbances, depressive moods, irritability, headaches, dizziness.

Dosage

1 tablet 2mg every other day or to 1 tablet 1mg daily. Under this lower dose, too, a tablet-free interval of at least 1 week should be observed after each 21-day regimen

Contra-Indications

-Known or suspected breast cancer. -Known or suspected estrogen-dependent neoplasms. -Undiagnosed vaginal bleeding. -Active or history of thromboembolic disorders (e.g., deep vein thrombosis, pulmonary embolism). -Liver dysfunction or disease. -Pregnancy.

Special Precautions

-Monitor for signs of thromboembolic events, especially in individuals with risk factors. -Use the lowest effective dose for the shortest duration consistent with treatment goals. -Regular monitoring and follow-up with a healthcare provider. -May increase the risk of breast cancer; regular breast exams and mammograms are recommended.

Side Effects

In rare cases, a feeling of tension in the breasts, gastric upsets, nausea, headaches, increase in body weight, and uterine bleeding can occur

Drug Interactions

-Estradiol Valerate may interact with certain medications, including anticoagulants, corticosteroids, and certain antiepileptic drugs. -Always consult a healthcare provider before starting or stopping any medication while taking estradiol valerate.