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Ethambutol

Ethambutol

It is well absorbed through Gastro Intestinal Tract and has a long half life. Since it inhibits the growth of M. tuberculosis, use in conjugation with other anti tubercular is considered valuable

Indications

Tuberculosis


Dosage

15 mg/kg body wt daily as single dose Retreatment : 25 mg/kg body wt. as single dose for 60 days, then 15 mg/kg body wt. to be administered with other anti-tubercular medicines.


Contra-Indications

Hypersensitivity. Optic neuritis, Liver damage. Susceptibility to epilepsy.


Special Precautions

Test visual functions before starting followed by periodic assessment of visual fields treatment. Impaired renal function. Paediatrics: Not prescribed under age of 6 years. Pregnancy: Safety not established. Lactation: Use with caution. Elderly: Reduced dose may be necessary.


Side Effects

Dose related adverse effect of retrobulbar neuritis of which the first signs are blurred vision and an inability to distinguish colours.


Drug Interactions

Absorption reduced by aluminium hydroxide.


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