Ethambutol
It is well absorbed through Gastro Intestinal Tract and has a long half life. Since it inhibits the growth of M. tuberculosis, use in conjugation with other anti tubercular is considered valuableTuberculosis
15 mg/kg body wt daily as single dose Retreatment : 25 mg/kg body wt. as single dose for 60 days, then 15 mg/kg body wt. to be administered with other anti-tubercular medicines.
Hypersensitivity. Optic neuritis, Liver damage. Susceptibility to epilepsy.
Test visual functions before starting followed by periodic assessment of visual fields treatment. Impaired renal function. Paediatrics: Not prescribed under age of 6 years. Pregnancy: Safety not established. Lactation: Use with caution. Elderly: Reduced dose may be necessary.
Dose related adverse effect of retrobulbar neuritis of which the first signs are blurred vision and an inability to distinguish colours.
Absorption reduced by aluminium hydroxide.
