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FAVIPIRAVIR

FAVIPIRAVIR

Favipiravir-RTP binds to and inhibits RNA-dependent RNA polymerase (RdRp), which ultimately prevents viral transcription and replication.

Indications

It is indicated among adults (age equal or greater then18years) in the treatment of mild to moderate cases of covid-19.


Dosage

Oral; 1800mg twice daily for first day than 800mg twice daily for maximum period of 14 days.


Contra-Indications

Pregnancy, lactating women, severe renal impairment, severe hepatic impairment, hypersensitivity to active substance.


Special Precautions

Paediatric: Not studied in pediatrics age group. Pregnancy: Contraindicated. Lactation: Contraindicated. Elderly: use with caution.


Side Effects

Increased blood uric acid level, diarrhea, decrease of neutrophil count, increased SGOT, increased SGPT.


Drug Interactions

Pyrazinamide, repaglinide, theophylline, sulindac, famciclovir.


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