Fluorometholone
Fluorometholone belongs to the class of corticosteroids and is available in ophthalmic preparations. It works by reducing inflammation and suppressing the immune response in the eyes. It is a corticosteroid which inhibits inflammatory response to a variety of inciting agents and probably delays or slows healing. Fluorometholone suspension inhibits the oedema, fibrin deposition, capillary dilation, leukocyte migration, capillary proliferation, deposition of collagen and scar formation associated with inflammation.-Fluorometholone is indicated for the treatment of inflammatory eye conditions, such as allergic conjunctivitis, iritis, uveitis, and certain types of keratitis. It helps alleviate symptoms like redness, swelling, itching, and discomfort. -Treatment of corticosteroid responsive inflammation of the palpebral and bulbar conjunctiva, cornea and anterior segment of the eye.
-The dosage of fluorometholone varies depending on the specific eye condition being treated. It is typically administered as eye drops, and the frequency and duration of use should be determined by a healthcare professional. Patients should follow the prescribed dosage instructions carefully. -Instill one drop into the conjunctival sac two to four times daily.During the initial 24 to 48 hours, the dosage may be increased to one application every four hours.
-Fluorometholone is contraindicated in individuals with a known hypersensitivity or allergy to corticosteroids. It should not be used in the presence of untreated bacterial, viral, or fungal eye infections. -Viral diseases of the cornea and conjunctiva, including epithelial herps simplex keratitis, vaccinia, varicella, and also in mycobacterial infection of ocular structures.
-Patients should inform their healthcare provider of any existing medical conditions, especially diabetes or glaucoma. -Prolonged use may lead to increased intraocular pressure, and regular monitoring is essential. -Contact lens wearers should remove lenses before applying eye drops and wait at least 15 minutes before reinserting them. -Pregnancy, lactation, Paediatric use : safety and effectiveness in children below the age of two years have not been established.
-Common side effects may include temporary stinging or burning upon application, blurred vision, and increased sensitivity to light. Prolonged use may lead to more severe side effects, such as cataracts or glaucoma. -Elevation of intraocular pressure with possibility of glaucoma and infrequent optic nerve damage, posterior subcapsular cataract formation and delayed wound healing.
Fluorometholone may interact with other medications, including oral corticosteroids or immunosuppressive drugs. Patients should inform their healthcare provider about all medications, including over-the-counter drugs and herbal supplements.
