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Glycerol

Glycerol

Glycerol, also known as glycerin, is a simple polyol compound that is colorless, odorless, and viscous. It is widely used in pharmaceutical formulations due to its properties as a humectant, solvent, and sweetener. Glycerol is often utilized in skin care products, cough syrups, and as a laxative in suppository form.

Indications

-Used as a humectant in skin care products to maintain moisture. -Employed as a sweetener and solvent in pharmaceuticals. -Administered as a laxative for relieving constipation. -Utilized in medical and personal care products such as toothpaste, mouthwashes, and cough syrups.


Dosage

-Oral dosage (as a laxative): For adults and children over 12 years, 15-30 ml as a single dose. -Rectal dosage (as a suppository): For adults, 1 suppository once daily as needed. -Dosage for other uses should be determined by a healthcare professional


Contra-Indications

-Hypersensitivity to glycerol or any component of the formulation. -Severe dehydration or electrolyte imbalance. -In patients with kidney or heart problems without medical supervision.


Special Precautions

-Use with caution in patients with diabetes as glycerol may affect blood glucose levels. -Ensure adequate hydration when using glycerol, especially as a laxative. -Not recommended for long-term use as a laxative without medical advice. -Monitor for signs of allergic reactions, such as rash, itching, or swelling.


Side Effects

-Common: Diarrhea, abdominal cramps, nausea, headache, dizziness. -Rare: Allergic reactions, difficulty breathing, swelling of the face, lips, tongue, or throat.


Drug Interactions

-May interact with other laxatives or medications affecting electrolyte balance. -Can affect the absorption of oral medications; consult a healthcare provider before combining with other treatments.


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