Guaiphenesin, Bromhexine, Terbutaline

Guaiphenesin, Bromhexine, and Terbutaline are medications commonly used in combination to treat respiratory conditions. Guaiphenesin is an expectorant, Bromhexine is a mucolytic agent, and Terbutaline is a bronchodilator. Together, they help relieve cough, thin mucus, and open airways.

Indications

-Relief of cough associated with bronchitis, asthma, and other respiratory conditions. -Facilitates expectoration of mucus. -Alleviates symptoms of bronchospasm.

Dosage

-Adults and children over 12 years: Typically, 5-10 ml of syrup containing the combination of these medications, taken orally 3-4 times daily. -Children 6-12 years: 2.5-5 ml, taken orally 3 times daily. -Children 2-6 years: 2.5 ml, taken orally 2-3 times daily. -Dosage may vary based on specific product formulations and patient conditions. Always follow physician recommendations.

Contra-Indications

-Hypersensitivity to Guaiphenesin, Bromhexine, Terbutaline, or any excipients in the formulation. -Severe hypertension or heart disease (due to Terbutaline). -Active peptic ulcer (caution with Bromhexine).

Special Precautions

-Use with caution in patients with cardiovascular disorders, hyperthyroidism, diabetes mellitus, and those prone to seizures (due to Terbutaline). -Not recommended for long-term use without medical supervision. -Adjust dosage for elderly patients with comorbidities. -Caution in pregnant and breastfeeding women; consult a healthcare provider.

Side Effects

-Common: Nausea, vomiting, headache, dizziness, tremors, palpitations. -Less common: Rash, diarrhea, increased heart rate, muscle cramps, anxiety.

Drug Interactions

-Beta-blockers: May reduce the efficacy of Terbutaline. -MAO inhibitors and tricyclic antidepressants: May potentiate the effects of Terbutaline. -Other cough and cold medications: Risk of additive effects or increased side effects. -Diuretics and corticosteroids: May increase the risk of hypokalemia with Terbutaline.