HIGHLY PURIFIED BROVIN PORCIN INSULIN ZINC SUSPENSION

Highly Purified Brovin Porcin Insulin Zinc Suspension is a long-acting insulin formulation derived from porcine (pig) insulin. This insulin suspension is combined with zinc to prolong its duration of action, making it suitable for maintaining basal insulin levels.

Indications

This medication is indicated for the management of diabetes mellitus in patients who require insulin to control hyperglycemia. It is particularly useful in cases where long-acting insulin is needed to maintain stable blood glucose levels throughout the day and night.

Dosage

-Adults and Children: The dosage should be individualized based on the patient's metabolic needs, blood glucose monitoring results, and glycemic control goal. Typically administered once or twice daily. -Adjustment: Dosage adjustments may be necessary during changes in physical activity, changes in meal patterns, concomitant illness, or changes in renal or hepatic function.

Contra-Indications

-Hypersensitivity to porcine insulin or any of the excipients in the formulation. -Hypoglycemia or conditions predisposing to hypoglycemia. -Not for intravenous administration.

Special Precautions

-Monitor blood glucose levels regularly to avoid hypoglycemia or hyperglycemia. -Use with caution in patients with renal or hepatic impairment. -Insulin requirements may be altered during periods of increased stress, illness, or surgical procedures. -Ensure proper patient education on self-administration techniques and recognition of hypoglycemia signs. -Pregnant or breastfeeding women should consult their healthcare provider before use.

Side Effects

-Common: Hypoglycemia, injection site reactions (redness, swelling, itching). -Less Common: Lipodystrophy at the injection site, allergic reactions (rash, pruritus). -Rare: Severe hypersensitivity reactions, including anaphylaxis.

Drug Interactions

-Hypoglycemic agents: Enhanced hypoglycemic effect (e.g., sulfonylureas, metformin). -Beta-blockers: May mask signs of hypoglycemia. -Corticosteroids, diuretics, and sympathomimetics: May increase blood glucose levels, requiring dose adjustment. -Alcohol: May either potentiate or weaken the hypoglycemic effect.