HUMAN ALBUMIN

Human albumin is a blood plasma protein derived from human blood. It plays a vital role in maintaining blood volume and pressure by acting as a carrier for various substances and regulating fluid distribution in the body. It is available in various concentrations, typically as 5% or 25% solutions, and can be administered intravenously.

Indications

Hypovolaemic shock. Normovolaemic haemodilution burns, plasma exchange, Neonatal jaundice.

Dosage

Shock: 100-200 ml; Children: 1-2 ml/kg body wt. Burns: 200- 400 ml on 1 st day followed by 100-200 ml. Children: 2-4 ml/kg body wt. Neonatal jaundice: 10-15 ml with exchange transfusion. Do not exceed 20 drops/ min.

Contra-Indications

Volume overload. Asystolia, circulatory failure. Hypersense.

Special Precautions

Dehydration: Use with rehydrating soln. Circulatory failure: monitor central venous pressure. Nephritis. Old age. Children.

Side Effects

Headache Nausea Fever Flushing Hives Vomiting

Drug Interactions

Human albumin can potentially interact with other medications that affect fluid balance or blood volume. Monitor patients closely when using albumin in conjunction with other drugs that may influence heart or kidney function.