Hydrocortisone

Hydrocortisone is a corticosteroid medication used to treat various conditions such as inflammation, immune system disorders, and adrenal insufficiency. It is available in different forms including tablets, injections, creams, and suppositories, depending on the condition being treated. Hydrocortisone works by mimicking the effects of cortisol, a natural hormone produced by the adrenal glands, to reduce inflammation and suppress the immune system.

Indications

Inflammatory and autoimmune conditions

Dosage

-Oral: 20-240 mg per day in divided doses -Topical: Apply a thin layer 1-4 times per day to the affected area -Injectable: Dosages vary, ranging from 25-500 mg depending on the condition and route of administration

Contra-Indications

-Hypersensitivity to the drug or any of its components -Systemic fungal infections -Live vaccines (if used at high doses)

Special Precautions

-Increased risk of infections due to immunosuppression -Adrenal suppression, especially with long-term use -Blood sugar and blood pressure levels (may cause increases)

Side Effects

-Weight gain and fluid retention -Mood changes (e.g., irritability, anxiety) -Skin thinning and increased susceptibility to bruising

Drug Interactions

-Nonsteroidal anti-inflammatory drugs (NSAIDs), increasing the risk of gastrointestinal bleeding -Diuretics, increasing the risk of hypokalemia -Vaccines, which may be less effective